Hives ICD-10: L50.9
Often searched as: itchy red bumps on skin, raised welts on body, hives all over body, itchy skin that comes and goes, rash that moves around, hives after eating, allergic skin reaction, skin welts that disappear…
Clinical urgency level
Systems Affected
Severity Levels
mild
Few scattered welts resolving within hours, no systemic symptoms — manageable with over-the-counter antihistamines.
moderate
Widespread or recurring hives lasting more than 24–48 hours, significantly affecting daily life, requiring prescription antihistamines or evaluation.
severe
Hives with angioedema (swelling of lips, tongue, throat), difficulty breathing, or dizziness — constitutes anaphylaxis, a medical emergency requiring epinephrine.
Red Flags
- Swelling of lips, tongue, or throat
- Difficulty breathing or wheezing
- Dizziness or fainting
- Hives spreading rapidly over the entire body
- Hives lasting more than 6 weeks continuously (chronic urticaria)
- Painful welts or welts lasting more than 24 hours in the same spot (possible vasculitis)
Clinical Presentation
Urticaria — classic raised red welts on the skin
Source: Wikimedia Commons (CC BY-SA 3.0 )
Hives (urticaria) image gallery — DermNet NZ
View gallery on DermNet NZ (image gallery reference)When to See a Doctor
Call emergency services immediately if hives are accompanied by throat swelling, breathing difficulty, or feeling faint — this may be anaphylaxis. See a doctor if hives persist beyond a few days, keep coming back without a clear cause, or are associated with fever or joint pain. Hives lasting more than 6 weeks always require medical evaluation.
Differential Diagnosis
- Allergic urticaria (identifiable trigger)
- Urticarial vasculitis (hives lasting >24h, may bruise)
- Physical urticaria (cold, pressure, or exercise-triggered)
- Contact dermatitis
- Erythema multiforme (target lesions)
- Insect bite reactions
- Mastocytosis (rare)
Comorbidities
- Allergic asthma
- Allergic rhinitis
- Atopic dermatitis
- Food or drug allergies
- Thyroid autoimmune disease (in chronic spontaneous urticaria)
- Anxiety and depression (chronic hives have significant psychological burden)
Prognosis
Acute hives (lasting less than 6 weeks) typically resolve fully once the trigger is removed, with antihistamines providing rapid relief. Chronic spontaneous urticaria (lasting more than 6 weeks) affects 1% of the population — about 50% resolve within 1 year, but some cases persist for years. Omalizumab (Xolair) is highly effective for antihistamine-resistant chronic urticaria. Identifying and avoiding triggers is the most effective long-term strategy.
Detailed Overview
Tags

Analyze your skin and hair with AI
Instantly analyze your skin with AI and get personal recommendations.
- - Get instant skin analysis
- - Personalized results from AI

* The scan result is not a diagnosis. To obtain a diagnosis and a treatment recommendation, consult your doctor.
Explore more conditions
Learn about other skin and hair conditions.