Hives ICD-10: L50.9

Allergic skin reaction

Often searched as: itchy red bumps on skin, raised welts on body, hives all over body, itchy skin that comes and goes, rash that moves around, hives after eating, allergic skin reaction, skin welts that disappear…

Clinical urgency level

lowmediumhigh

Systems Affected

skinmucous membranesupper airways (in severe anaphylactic reactions)

Severity Levels

mild

Few scattered welts resolving within hours, no systemic symptoms — manageable with over-the-counter antihistamines.

moderate

Widespread or recurring hives lasting more than 24–48 hours, significantly affecting daily life, requiring prescription antihistamines or evaluation.

severe

Hives with angioedema (swelling of lips, tongue, throat), difficulty breathing, or dizziness — constitutes anaphylaxis, a medical emergency requiring epinephrine.

Red Flags

  • Swelling of lips, tongue, or throat
  • Difficulty breathing or wheezing
  • Dizziness or fainting
  • Hives spreading rapidly over the entire body
  • Hives lasting more than 6 weeks continuously (chronic urticaria)
  • Painful welts or welts lasting more than 24 hours in the same spot (possible vasculitis)

Clinical Presentation

Urticaria — classic raised red welts on the skin

Urticaria — classic raised red welts on the skin

Source: Wikimedia Commons (CC BY-SA 3.0 )

Hives (urticaria) image gallery — DermNet NZ

View gallery on DermNet NZ (image gallery reference)

When to See a Doctor

Call emergency services immediately if hives are accompanied by throat swelling, breathing difficulty, or feeling faint — this may be anaphylaxis. See a doctor if hives persist beyond a few days, keep coming back without a clear cause, or are associated with fever or joint pain. Hives lasting more than 6 weeks always require medical evaluation.

Differential Diagnosis

  • Allergic urticaria (identifiable trigger)
  • Urticarial vasculitis (hives lasting >24h, may bruise)
  • Physical urticaria (cold, pressure, or exercise-triggered)
  • Contact dermatitis
  • Erythema multiforme (target lesions)
  • Insect bite reactions
  • Mastocytosis (rare)

Comorbidities

  • Allergic asthma
  • Allergic rhinitis
  • Atopic dermatitis
  • Food or drug allergies
  • Thyroid autoimmune disease (in chronic spontaneous urticaria)
  • Anxiety and depression (chronic hives have significant psychological burden)

Prognosis

Acute hives (lasting less than 6 weeks) typically resolve fully once the trigger is removed, with antihistamines providing rapid relief. Chronic spontaneous urticaria (lasting more than 6 weeks) affects 1% of the population — about 50% resolve within 1 year, but some cases persist for years. Omalizumab (Xolair) is highly effective for antihistamine-resistant chronic urticaria. Identifying and avoiding triggers is the most effective long-term strategy.

Detailed Overview

Causes, Symptoms, and When to Take Action Hives, or urticaria, are itchy, raised welts on the skin that appear suddenly and often disappear within hours. They are a common allergic skin reaction. How It Looks Texture: Raised, swollen patches or welts (wheals) Color: Red or skin-colored Shape: Round or irregular; individual welts change shape, move, merge, or fade and reappear elsewhere Location: Can appear anywhere on the body; may shift over time Why Does It Appear? Triggered by many possible causes: allergens (foods, medications), insect stings, infections, physical factors (heat, cold, pressure), stress. The reaction happens when certain cells in the skin release histamine and other chemicals, leading to swelling and itching. Should You Be Concerned? Most cases are harmless and resolve on their own. But see a doctor if: The welts persist for weeks or more (chronic hives) Swelling involves lips, tongue, or throat You have difficulty breathing or other systemic symptoms The rash is painful, widespread, or doesn't improve Can You Prevent It? Avoid known triggers whenever possible Maintain awareness of what you eat, medications you take, or environmental exposures Use loose clothing and avoid excessive heat or pressure in sensitive areas 👉 How Piel AI Can Help Piel AI can help you monitor how welts appear, change, and resolve over time through regular photos. While not diagnostic, it aids in recognizing patterns and determining when to seek care. Summary Hives are itchy, raised welts caused by a skin reaction to various triggers. They can appear anywhere, shift locations, and vary in shape and duration. Usually harmless, but persistent or severe cases require medical evaluation. Avoiding triggers and observing changes are key approaches.

Tags

itchy red bumps on skinraised welts on bodyhives all over bodyitchy skin that comes and goesrash that moves aroundhives after eatingallergic skin reactionskin welts that disappearhives treatment at homehives causeschronic hives won't go awayitchy bumps no reasonhives from stresshives photosred blotchy itchy skin
AI Agent Illustration

Analyze your skin and hair with AI

Instantly analyze your skin with AI and get personal recommendations.

  • - Get instant skin analysis
  • - Personalized results from AI
Analyze my skin and hair
AI Agent Illustration

* The scan result is not a diagnosis. To obtain a diagnosis and a treatment recommendation, consult your doctor.

Explore more conditions

Learn about other skin and hair conditions.

View all conditions →